23 hasil untuk "Francesca Rollo"

Human Papillomavirus Oral Infection: Review of Methodological Aspects and Epidemiology

Eugenia Giuliani; Francesca Rollo; Maria Gabriella Donà dkk.

Pathogens, Vol. 10 No. 11 · 2021 · Inggris · DOAJ Scopus

Oral infection by Human Papillomavirus (HPV) has recently gained great attention because of its involvement in the development of a subset of head and neck squamous cell carcinoma. The role of specific Alpha-HPVs in this regard has been well established, whereas the contribution of other genera is…

Evaluation of HPV-Related Biomarkers in Anal Cytological Samples from HIV-Uninfected and HIV-Infected MSM

Francesca Rollo; Alessandra Latini; Massimo Giuliani dkk.

Pathogens, Vol. 10 No. 7 · 2021 · Inggris · DOAJ Scopus

Men who have sex with men (MSM) harbor the highest risk for anal carcinoma, mainly caused by Human Papillomavirus (HPV). The use of HPV-related biomarkers in the screening for this neoplasia is still debated. We assessed the association between high-risk (hr)HPV DNA, HPV16/18 DNA, hrHPV E6/E7 mRNA…

Evolving Profile of HPV-Driven Oropharyngeal Squamous Cell Carcinoma in a National Cancer Institute in Italy: A 10-Year Retrospective Study

Maria Gabriella Donà; Francesca Rollo; Barbara Pichi dkk.

Microorganisms, Vol. 8 No. 10 · 2020 · Inggris · DOAJ Scopus

Globally, 30% of oropharyngeal carcinomas (OPSCC) are caused by Human Papillomavirus (HPV). Recently, increasing incidence trends for HPV-driven OPSCC have been reported in many countries and changes in the typical HPV-positive OPSCC patient have been recorded, with an increase in the median age…

FAM19A4 and miR124-2 methylation status in human papillomavirus-driven and human papillomavirus-negative oropharyngeal squamous cell carcinomas

Maria Gabriella Donà; Eugenia Giuliani; Valentina Laquintana dkk.

Infectious Agents and Cancer, Vol. 20 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Background Scarce data exist on host gene methylation in oropharyngeal squamous cell carcinomas (OPCs), which are caused by human papillomavirus (HPV) in approximately 40% of cases. We analyzed the methylation status of two host genes involved in cervical carcinogenesis, FAM19A4 and…

Concurrent and Concordant Anal and Oral Human PapillomaVirus Infections Are Not Associated with Sexual Behavior in At-Risk Males

Francesca Rollo; Alessandra Latini; Maria Benevolo dkk.

Pathogens, Vol. 10 No. 10 · 2021 · Inggris · DOAJ Scopus

Men who have sex with men (MSM) harbor the highest prevalence of anal and oral Human Papillomavirus (HPV) infection, particularly if HIV-infected. We investigated anal and oral HPV infections in HIV-infected and HIV-uninfected MSM, to assess concurrent (HPV detected at both sites, irrespective of…

Author Correction: Incidence and clearance of anal high-risk Human Papillomavirus infection and their risk factors in men who have sex with men living with HIV

Maria Gabriella Donà; Massimo Giuliani; Francesca Rollo dkk.

Scientific Reports, Vol. 12 No. 1 · 2022 · Inggris · DOAJ Scopus

Incidence and clearance of anal high-risk Human Papillomavirus infection and their risk factors in men who have sex with men living with HIV

Maria Gabriella Donà; Massimo Giuliani; Francesca Rollo dkk.

Scientific Reports, Vol. 12 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract HIV-infected men who have sex with men (MSM) display the highest prevalence of anal infection by high-risk Human Papillomaviruses (hrHPVs) and incidence of anal carcinoma. Anal specimens were genotyped by the Linear Array. Incidence and clearance of anal infection by hrHPVs, hrHPVs other…

Correlation between histogram-based DCE-MRI parameters and 18 F-FDG PET values in oropharyngeal squamous cell carcinoma: Evaluation in primary tumors and metastatic nodes

Antonello Vidiri; Emma Gangemi; Emanuela Ruberto dkk.

PLOS ONE, Vol. 15 No. 3 · 2020 · Inggris · PLOS Scopus

Objectives: To investigate the correlation between histogram-based Dynamic Contrast-Enhanced magnetic resonance imaging (DCE-MRI) parameters and positron emission tomography with 18F-fluorodeoxyglucose (18F-FDG-PET) values in oropharyngeal squamous cell carcinoma (OPSCC), both in primary tumors…

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Prevalence and determinants of oral infection by Human Papillomavirus in HIV-infected and uninfected men who have sex with men

Francesca Rollo; Alessandra Latini; Barbara Pichi dkk.

PLOS ONE, Vol. 12 No. 9 · 2017 · Inggris · PLOS Scopus

Background: Oral Human Papillomavirus (HPV) infection is rare in the general population but common in high-risk individuals. Recent data indicate that oral HPV is associated with the development of head and neck carcinomas. HPV16 infection, in particular, increases the risk of oropharyngeal cancer…

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A cut-off of 2150 cytokeratin 19 mRNA copy number in sentinel lymph node may be a powerful predictor of non-sentinel lymph node status in breast cancer patients

Irene Terrenato; Valerio D’Alicandro; Beatrice Casini dkk.

PLOS ONE, Vol. 12 No. 2 · 2017 · Inggris · PLOS Scopus

Since 2007, one-step nucleic acid amplification (OSNA) has been used as a diagnostic system for sentinel lymph node (SLN) examination in patients with breast cancer. This study aimed to define a new clinical cut-off of CK19 mRNA copy number based on the calculation of the risk that an axillary…

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Microbiome analysis in individuals with human papillomavirus oral infection

David Israel Escobar Marcillo; Grete Francesca Privitera; Francesca Rollo dkk.

Scientific Reports, Vol. 15 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Microbiome gained attention as a cofactor in cancers originating from epithelial tissues. High-risk (hr)HPV infection causes oropharyngeal squamous cell carcinoma but only in a fraction of hrHPV+ individuals, suggesting that other factors play a role in cancer development. We investigated…

Multifactorial Model Based on DWI-Radiomics to Determine HPV Status in Oropharyngeal Squamous Cell Carcinoma

Simona Marzi; Francesca Piludu; Ilaria Avanzolini dkk.

Applied Sciences, Vol. 12 No. 14 · 2022 · Inggris · DOAJ Scopus

Background: Oropharyngeal squamous cell carcinoma (OPSCC) associated with human papillomavirus (HPV) has higher rates of locoregional control and a better prognosis than HPV-negative OPSCC. These differences are due to some unique biological characteristics that are also visible through advanced…

Prevalence of 13 polyomaviruses in actinic keratosis and matched healthy skin samples of immunocompetent individuals

Maria Gabriella Donà; Tarik Gheit; Maria Vincenza Chiantore dkk.

Infectious Agents and Cancer, Vol. 17 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract Background Actinic keratosis (AK) is a precursor of cutaneous squamous cell carcinoma (cSCC). UV radiation is the major risk factor for AK, but certain human papillomaviruses (HPVs) of the beta genus are also involved in its development. Differently, the role of polyomaviruses (PyVs) in…

The Glioma-IRE project − Molecular profiling in patients with glioma: steps toward an individualized diagnostic and therapeutic approach

Veronica Villani; Beatrice Casini; Antonio Tanzilli dkk.

Journal of Translational Medicine, Vol. 21 No. 1 · 2023 · Inggris · DOAJ Scopus

Abstract Background This study aimed to characterize the genetic profile of patients with glioma and discuss the impact of next-generation sequencing in glioma diagnosis and treatment. Methods Between 2019 and 2022, we analyzed the genetic profile of 99 patients with glioma through the Oncomine…

Oral Infection by Mucosal and Cutaneous Human Papillomaviruses in the Men Who Have Sex with Men from the OHMAR Study

Tarik Gheit; Francesca Rollo; Rosario N Brancaccio dkk.

Viruses, Vol. 12 No. 8 · 2020 · Inggris · DOAJ Scopus

Both mucosal and cutaneous Human Papillomaviruses (HPVs) can be detected in the oral cavity, but investigations regarding the epidemiology of cutaneous HPVs at this site are scarce. We assessed mucosal (alpha) and cutaneous (beta and gamma) HPV infection in oral samples of HIV-infected and…

Correction: Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer

Federica Ganci; Matteo Allegretti; Carlotta Frascolla dkk.

Biomarker Research, Vol. 12 No. 1 · 2024 · Inggris · DOAJ Scopus

Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer

Federica Ganci; Matteo Allegretti; Carlotta Frascolla dkk.

Biomarker Research, Vol. 12 No. 1 · 2024 · Inggris · DOAJ Scopus

Abstract Locoregional recurrences represent a frequently unexpected problem in head and neck squamous cell carcinoma (HNSCC). Relapse often (10–30%) occurs in patients with histologically negative resection margins (RMs), probably due to residual tumor cells or hidden pre-cancerous lesions in…