33 hasil untuk "Li-Da Chen"

Electrochemical Detection of Electrolytes Using a Solid-State Ion-Selective Electrode of Single-Piece Type Membrane

Li-Da Chen; Wei-Jhen Wang; Gou-Jen Wang

Biosensors, Vol. 11 No. 4 · 2021 · Inggris · DOAJ Scopus

This study aimed to develop simple electrochemical electrodes for the fast detection of chloride, sodium and potassium ions in human serum. A flat thin-film gold electrode was used as the detection electrode for chloride ions; a single-piece type membrane based solid-state ion-selective electrode…

The complete plastome of Syzygium odoratum (Lour.) DC. 1928 (Myrtaceae)

Li-Da Chen; Hua-Feng Wang; De-Jia Hou

Mitochondrial DNA. Part B. Resources, Vol. 7 No. 4 · 2022 · Inggris · DOAJ Scopus

Syzygium odoratum (Lour.) DC. 1828 is a deciduous shrub in the family Myrtaceae. This species grows in sparse forests, especially in mountains, valleys, and broad-leaved evergreen forests along streams from 100 to 400 m above sea level. The primary distribution is in southern China (e.g. Guangdong…

Effect of Continuous Positive Airway Pressure on Adiponectin in Patients with Obstructive Sleep Apnea: A Meta-Analysis

Li-Da Chen; Jian-Nan Liu; Li Lin dkk.

PLOS ONE, Vol. 10 No. 9 · 2015 · Inggris · PLOS Scopus

Objective: Obstructive sleep apnea (OSA) has been suggested to be associated with low levels of adiponectin. Continuous positive airway pressure (CPAP) is the gold standard treatment for OSA; however, previous studies assessing the effect of CPAP on adiponectin in patients with OSA yielded…

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Prediction of lymph node metastasis in rectal cancer: comparison between shear-wave elastography based ultrasomics and MRI

Meng-Fei Xian; Xin Zheng; Jian-Bo Xu dkk.

Diagnostic and Interventional Radiology, Vol. 27 No. 3 · 2021 · Inggris · DOAJ Scopus

PURPOSEWe aimed to explore the diagnostic efficiency of shear-wave elastography (SWE) ultrasomics in the preoperative prediction of lymph node (LN) metastasis in rectal cancer.METHODSThis study included 87 patients with pathologically confirmed rectal cancer, with data gathered from August 2017 to…

Effect of continuous positive airway pressure on carotid intima-media thickness in patients with obstructive sleep apnea: A meta-analysis

Li-Da Chen; Li Lin; Xue-Jun Lin dkk.

PLOS ONE, Vol. 12 No. 9 · 2017 · Inggris · PLOS Scopus

Objective: Obstructive sleep apnea (OSA) is associated with increased carotid intima-media thickness (IMT), an early marker of atherosclerosis. Continuous positive airway pressure (CPAP) is the first-line treatment for OSA. A meta-analysis was performed to determine whether CPAP therapy could…

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Untargeted Metabolomic Profiling of Liver in a Chronic Intermittent Hypoxia Mouse Model

Li-Da Chen; Zhi-Wei Huang; Yu-Zhen Huang dkk.

Frontiers in Physiology, Vol. 12 · 2021 · Inggris · DOAJ Scopus

…MS and orthogonal partial least squares-discriminant analysis (OPLS-DA) were applied to screen altered metabolites in mice liver. Bioinformatics analyses were applied to identify the related metabolic pathways. CIH treatment caused a remarkable liver injury in mice. A total of 27 differential…

Role of serum IL-6 and TNF-α in coronavirus disease 2019 (COVID-19) associated renal impairment

Li-Da Chen; Lan Hu; Yang Song dkk.

European Journal of Inflammation, Vol. 20 · 2022 · Inggris · DOAJ Scopus

Objectives: Association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and kidney injury has been noted in previous studies. However, the mechanisms remain unknown. The present study aimed to explore the potential mechanisms of kidney injury in COVID-19. Methods…

A COVID-19 patient with multiple negative results for PCR assays outside Wuhan, China: a case report

Li-Da Chen; Hao Li; Yu-Ming Ye dkk.

BMC Infectious Diseases, Vol. 20 No. 1 · 2020 · Inggris · DOAJ Scopus

Abstract Background The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a public health emergency of major international concern. Real-time RT-PCR assays are recommended for diagnosis of COVID-19. Here we report a…

Relationship between Obstructive Sleep Apnea and Liver Abnormalities in Older Patients: A Cross-Sectional Study

Yong-Xu Jin; Bi-ying Wang; Xiao-li Wang dkk.

International Journal of Clinical Practice, Vol. 2023 · 2023 · Inggris · DOAJ Scopus

Background. Older age is a risk factor for obstructive sleep apnea (OSA), which is associated with the development of nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the correlation between OSA and liver injury among older patients. Study Design. This is a cross-sectional study…

Identification of key genes in chronic intermittent hypoxia-induced lung cancer progression based on transcriptome sequencing

Li-Da Chen; Li Lin; Ji-Zhi Chen dkk.

BMC Cancer, Vol. 24 No. 1 · 2024 · Inggris · DOAJ Scopus

Abstract Background Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer mortality. Nevertheless, little is known about the underlying molecular mechanisms. This research aimed to investigate differentially expressed genes (DEGs) and explore their function in Lewis lung…

Single-nucleus RNA sequencing uncovers cell type-specific alterations in OSA-related liver injury

Wen-Sen Huang; Chao-Qiang Wang; Yu-Zhen Huang dkk.

Scientific Reports, Vol. 16 No. 1 · 2026 · Inggris · DOAJ Scopus

Abstract Chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA), is strongly implicated in the development of hepatic injury. However, the cellular mechanisms underlying CIH-induced liver dysfunction remain poorly understood. This study aimed to systematically…

Risk factors for mortality of coronavirus disease-2019 (COVID-19) patients in two centers of Hubei province, China: A retrospective analysis

Xiao-Bin Zhang; Lan Hu; Quan Ming dkk.

PLOS ONE, Vol. 16 No. 1 · 2021 · Inggris · PLOS Scopus

Purpose: Since the outbreak in late December 2019 in Wuhan, China, coronavirus disease-2019 (COVID-19) has become a global pandemic. We analyzed and compared the clinical, laboratory, and radiological characteristics between survivors and non-survivors and identify risk factors for mortality…

Association between cytokine profiles and lung injury in COVID-19 pneumonia

Li-Da Chen; Zhen-Yu Zhang; Xiao-Jie Wei dkk.

Respiratory Research, Vol. 21 No. 1 · 2020 · Inggris · DOAJ Scopus

Abstract Background Coronavirus disease 2019 (COVID-19) is a new respiratory and systemic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The purpose of the present study was to investigate the association between cytokine profiles and lung injury in…

Single-nucleus transcriptome profiling provides insights into the pathophysiology of OSA-related renal injury

Ya-Ping Huang; Zhi-Wei Huang; Yu-Zhen Huang dkk.

Scientific Reports, Vol. 15 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Obstructive sleep apnea (OSA) has been demonstrated to be associated with renal injury. However, the cellular and molecular mechanisms by which chronic intermittent hypoxia (CIH), a hallmark of OSA, contributes to renal injury remain poorly understood. Twelve male Sprague-Dawley rats were…

Correction to: Differentiation between combined hepatocellular cholangiocarcinoma and hepatocellular carcinoma: comparison of diagnostic performance between ultrasomics-based model and CEUS LI-RADS v2017

Chao-qun Li; Xin Zheng; Huan-ling Guo dkk.

BMC Medical Imaging, Vol. 22 No. 1 · 2022 · Inggris · DOAJ Scopus

Differential diagnosis between hepatic alveolar echinococcosis and intrahepatic cholangiocarcinoma with conventional ultrasound and contrast-enhanced ultrasound

Zeng-Cheng Wa; Ting Du; Xian-Feng Li dkk.

BMC Medical Imaging, Vol. 20 No. 1 · 2020 · Inggris · DOAJ Scopus

Abstract Background Misclassifications of hepatic alveolar echinococcosis (HAE) as intrahepatic cholangiocarcinoma (ICC) may lead to inappropriate treatment strategies. The aim of this study was to explore the differential diagnosis with conventional ultrasound and contrast-enhanced ultrasound…

Differentiation between combined hepatocellular carcinoma and hepatocellular carcinoma: comparison of diagnostic performance between ultrasomics-based model and CEUS LI-RADS v2017

Chao-qun Li; Xin Zheng; Huan-ling Guo dkk.

BMC Medical Imaging, Vol. 22 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract Background The imaging findings of combined hepatocellular cholangiocarcinoma (CHC) may be similar to those of hepatocellular carcinoma (HCC). CEUS LI-RADS may not perform well in distinguishing CHC from HCC. Studies have shown that radiomics has an excellent imaging analysis ability. This…

Exploring hepatic fibrosis screening via deep learning analysis of tongue images

Xiao-zhou Lu; Hang-tong Hu; Wei Li dkk.

Journal of Traditional and Complementary Medicine, Vol. 14 No. 5 · 2024 · Inggris · DOAJ Scopus

Background: Tongue inspection, an essential diagnostic method in Traditional Chinese Medicine (TCM), has the potential for early-stage disease screening. This study aimed to evaluate the effectiveness of deep learning-based analysis of tongue images for hepatic fibrosis screening. Methods: A total…