39 hasil untuk "Li-Li, Guo"
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Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of tulathromycin against Haemophilus parasuis in an experimental neutropenic guinea pig model
The objective of the study was to develop an ex-vivo PK/PD model of intramuscular (IM) administration of tulathromycin and to test its efficacy against Haemophilus parasuis (H. parasuis) infection in intraperitoneal-inoculated neutropenic guinea pigs. The pharmacokinetics (PKs) of tulathromycin at…
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In vivo Pharmacokinetic/Pharmacodynamic (PK/PD) Profiles of Tulathromycin in an Experimental Intraperitoneal Haemophilus parasuis Infection Model in Neutropenic Guinea Pigs
Tulathromycin is a semi-synthetic macrolide antimicrobial that has an important role in veterinary medicine for respiratory disease. The objective of the study was to develop a pharmacokinetic/pharmacodynamic (PK/PD) model to examine the efficacy and determine an optimal dosage of tulathromycin…
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A New Titanosaurian Sauropod from the Hekou Group (Lower Cretaceous) of the Lanzhou-Minhe Basin, Gansu Province, China
Increased excavation of dinosaurs from China over the last two decades has enriched the record of Asian titanosauriform sauropods. However, the relationships of these sauropods remain contentious, and hinges on a few well-preserved taxa, such as Euhelopus zdanskyi. Here we describe a new sauropod…
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Pelvic reconstruction improves pelvic floor strength in pelvic organ prolapse patients
Objective: To evaluate pelvic floor muscle strength after the modified pelvic reconstruction procedure for pelvic organ prolapse (POP). Materials and methods: Patients were assigned to two groups consisting of 37 patients diagnosed with POP and undergoing modified pelvic reconstruction…
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Age-related analysis of corneal biomechanical parameters in healthy Chinese individuals
Abstract To report the correlation between corneal biomechanical parameters and age in healthy Chinese individuals. This cross-sectional study was conducted on 864 eyes of 543 healthy participants. A comprehensive ophthalmic examination and corneal biomechanics examination using Corneal…
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Ethyl 6-(4-fluorophenyl)-4-hydroxy-2-oxo-4-trifluoromethyl-1,3-diazinane-5-carboxylate monohydrate
The asymmetric unit of the title compound, C14H14F4N2O4·H2O, contains two crystallographically independent organic molecules and two water molecules. The two 1,3-diazinane rings adopt a half-chair conformation and the dihedral angles between their mean planes and those of the benzene rings are…
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[20(22)E]-Lanostane Triterpenes from the Fungus Ganoderma australe
Twelve new lanostane triterpenoids (1–5, 7–13) were isolated from the fruiting bodies of the fungus Ganoderma australe. The structures of the new compounds were elucidated by extensive 1D and 2D NMR, and HRESIMS spectroscopic analysis. All the triterpenes are featured by 20(22)E configurations…
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Identification and validation of a m7G-related lncRNA signature for predicting the prognosis and therapy response in hepatocellular carcinoma
Background: N7-methylguanosine (m7G) is one of the most common RNA posttranscriptional modifications; however, its potential role in hepatocellular carcinoma (HCC) remains unknown. We developed a prediction signature based on m7G-related long noncoding RNAs (lncRNAs) to predict HCC prognosis and…
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Enhanced recovery after surgery in laparoscopic radical gastrectomy for gastric cancer: efficacy, safety, meta-analysis
Abstract Objective To systematically evaluate the efficacy and safety of enhanced recovery after surgery (ERAS) involving laparoscopic radical gastrectomy for gastric cancer (GC). Methods A systematic literature search was conducted across four English databases (PubMed, the Cochrane Library…
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Prediction of histopathological grade in gastric cancer using dual energy CT-derived synthetic extracellular volume fraction
PurposeTo investigate the relationship between the synthetic extracellular volume (ECV) fraction and the hematocrit (HCT)-based ECV fraction in gastric cancer patients and to evaluate its potential utility in predicting the pathological grade of gastric cancer.MethodsData from the derivation cohort…
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In Vivo Corneal Biomechanical Properties in a Selected Chinese Population, Measured Using the Corneal Visualization Scheimpflug Technology
Purpose: To evaluate the repeatability and reproducibility of recalculated dynamic corneal response (DCR) parameters and the biomechanical-compensated intraocular pressure (bIOP) derived from the Corneal Visualization Scheimpflug Technology (Corvis ST), as well as to study the variations of DCR…
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Study of simple plane wave generator with an air-metal barrier
Plane wave generators (PWGs) are used to accelerate flyer plates to high velocities with their generated plane waves, which are widely used in the test of dynamic properties of materials. The traditional PWG is composed of two explosives with different detonation velocities. It is difficult to…
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Transcriptome analysis reveals mechanism of early ripening in Kyoho grape with hydrogen peroxide treatment
Abstract Background In a previous study, the early ripening of Kyoho grape following H2O2 treatment was explored at the physiological level, but the mechanism by which H2O2 promotes ripening at the molecular level is unclear. To reveal the molecular mechanism, RNA-sequencing analysis was conducted…
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Analysis on Risk Factors of Depressive Symptoms in Occupational Noise-induced Hearing Loss Patients: A Cross-sectional Study
Objective: The aim of this study was to evaluate the risk factors of depressive symptoms in occupational noise-induced hearing loss (NIHL) patients. Methods: A total of 106 patients were divided into depressive symptoms (ONHLPD) and without depressive symptoms (non-ONHLPD) according to the…
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Recombinant globular adiponectin relieves kidney injury in diabetic mice
Objective To investigate whether recombinant globular adiponectin can reduce kidney injury in diabetic mice by regulating autophagy and endoplasmic reticulum stress. Methods Mice were randomly divided into control group,diabetic model group, low and high dose of adiponectin group (5 and 15 μg/kg…
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Preparation and Properties of Indium Ion Modified Graphite Felt Composite Electrode
Iron-chromium redox flow batteries (ICRFBs) have the advantages of high safety, long cycle life, flexible design, and low maintenance costs. Polyacrylonitrile-based graphite felt composite material has good temperature resistance, corrosion resistance, large surface area and excellent electrical…