19 results for "Li-ming TAN"

Anticonvulsants Delaying the Diagnosis of Cushing′s syndrome in a Patient Who Presents with Schizophrenia

Xin Zhao; Harrison X Bai; Li-Ming Tan et al.

Chinese Medical Journal, Vol. 128 No. 5 · 2015 · English · DOAJ Scopus

Protective effects of endoplasmic reticulum stress preconditioning on hippocampal neurons in rats with status epilepticus

Yi ZHANG; Li-ming TAN; Xiao-wen JIANG et al.

Chinese Journal of Contemporary Neurology and Neurosurgery, Vol. 14 No. 12 · 2014 · Chinese · DOAJ Scopus

Objective To evaluate the protective effects of endoplasmic reticulum stress preconditioning induced by 2-deoxyglucose (2-DG) on hippocampal neurons of rats with status epilepticus (SE) and the possible mechanism. Methods Ninety Sprague-Dawley (SD) rats were randomly enrolled into preconditioning…

Stigmasterol ameliorates neurological deficits and neuroinflammation in rats with traumatic brain injury by suppressing STAT3/NF-κB/LCN-2

Jing-Yuan Zhou; Li-Ming Tan; Zhen-Yu Nie et al.

Chinese Journal of Traumatology, Vol. 29 No. 5 · 2026 · English · DOAJ Scopus

Purpose: TBI triggers intricate inflammatory processes that lead to secondary damage. Stig, a compound known for its cholesterol-lowering effects, demonstrates significant therapeutic potential, encompassing anti-cancer, antioxidant, and anti-atherosclerotic properties. It possesses an ability to…

Stroke-like Migraine Attacks after Radiation Therapy Syndrome

Qian Zheng; Li Yang; Li-Ming Tan et al.

Chinese Medical Journal, Vol. 128 No. 15 · 2015 · English · DOAJ Scopus

Objective: To summarize the clinical presentation, pathogenesis, neuroimaging, treatment, and outcome of stroke-like migraine attacks after radiation therapy (SMART) syndrome, and to propose diagnostic criteria for this disorder. Data Sources: We searched the PubMed database for articles in English…

The Role of MicroRNAs in Hyperlipidemia: From Pathogenesis to Therapeutical Application

Yu Xiang; Li Mao; Mei-Ling Zuo et al.

Mediators of Inflammation, Vol. 2022 · 2022 · English · DOAJ Scopus

Hyperlipidemia is a common metabolic disorder with high morbidity and mortality, which brings heavy burden on social. Understanding its pathogenesis and finding its potential therapeutic targets are the focus of current research in this field. In recent years, an increasing number of studies have…

Evidence-based clinical practice guideline for chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19 : evidence evaluation (1)

Ming-Zhen LI; Xia-Mei XU; Shao-Hua HE et al.

Yixue xinzhi zazhi, Vol. 30 No. 6 · 2020 · Chinese · DOAJ Scopus

Objective To re-evaluate the systematic evaluation of the evidence included in the team's published clinical practice guidelines for COVID-19 drug prevention, diagnosis, treatment, and discharge management.Methods we were electronically searched to collect systematic evaluation/meta-analysis of…

Pharmacoepitranscriptomic landscape revealing m6A modification could be a drug-effect biomarker for cancer treatment

Ke Liu; Qian-Ying Ouyang; Yan Zhan et al.

Molecular Therapy: Nucleic Acids, Vol. 28 · 2022 · English · DOAJ Scopus

RNA chemical modifications are a new but rapidly developing field. They can directly affect RNA splicing, transport, stability, and translation. Consequently, they are involved in the occurrence and development of diseases that have been studied extensively in recent years. However, few studies…

Second in the series of shared decision making: a model for shared decision making research, the Ottawa Patient Decision Aids Research Group

Shao-Fu YU; Wei MU; Ying-Hui JIN et al.

Yixue xinzhi zazhi, Vol. 31 No. 1 · 2021 · Chinese · DOAJ Scopus

The study of shared decision making (SDM) has been going on in the western countries for many decades, and representative research groups such as the Ottawa Patient Decision Aids Research Group, the Mayo Clinic Shared Decision Making National Resource Center and the National Institute for Health…

Genetic Polymorphisms and Platinum-based Chemotherapy Treatment Outcomes in Patients with Non-Small Cell Lung Cancer: A Genetic Epidemiology Study Based Meta-analysis

Li-Ming Tan; Cheng-Feng Qiu; Tao Zhu et al.

Scientific Reports, Vol. 7 No. 1 · 2017 · English · DOAJ Scopus

Abstract Data regarding genetic polymorphisms and platinum-based chemotherapy (PBC) treatment outcomes in patients with NSCLC are published at a growing pace, but the results are inconsistent. This meta-analysis integrated eligible candidate genes to better evaluate the pharmacogenetics of PBC in…

SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2

Ai Qing Yu; Jie Wang; Shi Tao Jiang et al.

Frontiers in Cell and Developmental Biology, Vol. 9 · 2021 · English · DOAJ Scopus

Dysregulation of protein posttranslational modification (PTM) can lead to a variety of pathological processes, such as abnormal sperm development, malignant tumorigenesis, depression, and aging process. SIRT7 is a NAD+-dependent protein deacetylase. Besides known deacetylation, SIRT7 may also have…

Asialoglycoprotein receptor 1 gene expression in peripheral blood monocytes associates with serum total cholesterol and low-density lipoprotein cholesterol levels

Xiang Zhao; Bin Tang; Zhi-Hua Shi et al.

Chinese Medical Journal, Vol. 133 No. 12 · 2020 · English · DOAJ Scopus

Potential significance of changes in serum levels of IL-17, TNF-α and DKK-1 in the progression of the rheumatoid arthritis

Qunxia Wang; Yanzhao Liu; Jiazhen Wu et al.

Autoimmunity, Vol. 56 No. 1 · 2023 · English · DOAJ Scopus

AbstractTo detect the value of serum interleukin-17 (IL-17), tumour necrosis factor-α (TNF-α), and Dickkopf-1 (DKK-1) in rheumatoid arthritis (RA) at different disease stages. 141 RA patients were randomly obtained and diagnosed in a large tertiary first-class hospital in Jiangxi Province from…

Prognostic value of circulating tumor cells in patients with non-small cell lung cancer: a Meta-analysis

Ming-Zhen LI; Shao-Hua HE; Ying-Hui JIN et al.

Yixue xinzhi zazhi, Vol. 32 No. 4 · 2022 · Chinese · DOAJ Scopus

Objective To systematically evaluate the prognostic value of circulating tumor cells (CTCs) in patients with non-small cell lung cancer (NSCLC).Methods We electronically searched CNIK, WanFang Data, CBM, VIP, PubMed, Web of Science, The Cochrane Library, and Embase database for literature regarding…

Determinants of successful guideline implementation: a national cross-sectional survey

Ying-hui Jin; Li-Ming Tan; Khalid S. Khan et al.

BMC Medical Informatics and Decision Making, Vol. 21 No. 1 · 2021 · English · DOAJ Scopus

Abstract Background CPGs are not uniformly successful in improving care and several instances of implementation failure have been reported. Performing a comprehensive assessment of the barriers and enablers is key to developing an informed implementation strategy. Our objective was to investigate…

Genetic Variants in Double-Strand Break Repair Pathway Genes to Predict Platinum-Based Chemotherapy Prognosis in Patients With Lung Cancer

Jun-Yan Liu; Ting Zou; Ji-Ye Yin et al.

Frontiers in Pharmacology, Vol. 13 · 2022 · English · DOAJ Scopus

Objective: The purpose of this study was to investigate the associations of genetic variants in double-strand break (DSB) repair pathway genes with prognosis in patients with lung cancer treated with platinum-based chemotherapy.Methods: Three hundred ninety-nine patients with lung cancer who…

Do medical staffs need to wear masks? - Arguments based on best evidence

Yun-Yun WANG; Ying-Juan CAO; Rong FU et al.

Yixue xinzhi zazhi, Vol. 30 No. 2 · 2020 · Chinese · DOAJ Scopus

Objective whether the medical staff need to wear masks or not is still controversial, the aim of this study is to evaluate and summarize the best evidence relevant to this topic in order to provide sugges-tions for the medical staff.Methods PubMed, Cochrane Library, web of science, CINAHL, CNKI…

Development and preliminary validation of questionnaire for 2019 novel coronavirus releated nosocomial infection

Yun-Yun WANG; Tong DENG; Bing-Hui LI et al.

Yixue xinzhi zazhi, Vol. 30 No. 3 · 2020 · Chinese · DOAJ Scopus

Objective To formulate the 2019 novel coronavirus (2019-nCoV) nosocomial infection research and analysis tools.Methods Based on the questionnaire for infection process and prevention of 2019-nCoV infection in medical staffs, we developed the new questionnaire by means of three procedures including…

Evidence-based Chinese expert recommendations on drug prevention，diagnosis, treatment, and discharge management of covid-19 a protocol

Ying-Hui JIN; Hong-Jun LI; Qing-Yuan ZHAN et al.

Yixue xinzhi zazhi, Vol. 30 No. 3 · 2020 · Chinese · DOAJ Scopus

This is the protocol of updated our previously guideline named “A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)”. This protocol included guideline methodology, target users, target population, conflict of interest…

Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline (updated version)

Ying-Hui Jin; Qing-Yuan Zhan; Zhi-Yong Peng et al.

Military Medical Research, Vol. 7 No. 1 · 2020 · English · DOAJ Scopus

Abstract The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis and treatment guidelines for clinicians caring for patients are…