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Artikel Jurnal Teks lengkap
Regulation of exosomes as biologic medicines: Regulatory challenges faced in exosome development and manufacturing processes
With advances in medical technology, extracellular vesicles, also known as exosomes, are gaining widespread attention because of their potential therapeutic applications. However, their regulatory landscape is complex and varies across countries because of their unique intracellular mechanisms of…
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RGD peptide in cancer targeting: Benefits, challenges, solutions, and possible integrin–RGD interactions
RGD peptide can be found in cell adhesion and signaling proteins, such as fibronectin, vitronectin, and fibrinogen. RGD peptides' principal function is to facilitate cell adhesion by interacting with integrin receptors on the cell surface. They have been intensively researched for use in…
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Management of Fatigue in Adult Survivors of Cancer: ASCO–Society for Integrative Oncology Guideline Update
ASCO–Society for Integrative Oncology (SIO) Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following the guideline development process as outlined in the ASCO Guidelines Methodology Manual . ASCO-SIO Guidelines follow…
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Global nitrous oxide budget (1980–2020)
Nitrous oxide (N 2 O) is a long-lived potent greenhouse gas and stratospheric ozone-depleting substance that has been accumulating in the atmosphere since the preindustrial period. The mole fraction of atmospheric N 2 O has increased by nearly 25 % from 270 ppb (parts per billion) in 1750 to 336…
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Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults
BACKGROUND: Many older adults with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) have a relapse despite having a measurable residual disease (MRD)-negative complete remission with combination chemotherapy. The addition of blinatumomab, a bispecific T-cell engager molecule that is approved…
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Artikel Jurnal Teks lengkap
The interplay of learning, analytics and artificial intelligence in education: A vision for hybrid intelligence
Abstract This paper presents a multidimensional view of AI's role in education, emphasising the intricate interplay among AI, analytics and human learning processes. Here, I challenge the prevalent narrow conceptualisation of AI as tools in Education, exemplified in generative AI tools, and argue…
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Phase 3 Trial of Stereotactic Body Radiotherapy in Localized Prostate Cancer
BACKGROUND: Whether stereotactic body radiotherapy (SBRT) is noninferior to conventionally or moderately hypofractionated regimens with respect to biochemical or clinical failure in patients with localized prostate cancer is unclear. METHODS: We conducted a phase 3, international, open-label…
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TreeViewer : Flexible, modular software to visualise and manipulate phylogenetic trees
Phylogenetic trees illustrate evolutionary relationships between taxa or genes. Tree figures are crucial when presenting results and data, and by creating clear and effective plots, researchers can describe many kinds of evolutionary patterns. However, producing tree plots can be a time-consuming…
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A Survey of Beam Management for mmWave and THz Communications Towards 6G
Communication in millimeter wave (mmWave) and even terahertz (THz) frequency bands is ushering in a new era of wireless communications. Beam management, namely initial access and beam tracking, has been recognized as an essential technique to ensure robust mmWave/THz communications, especially for…
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Feedback sources in essay writing: peer-generated or AI-generated feedback?
Abstract Peer feedback is introduced as an effective learning strategy, especially in large-size classes where teachers face high workloads. However, for complex tasks such as writing an argumentative essay, without support peers may not provide high-quality feedback since it requires a high level…
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Enhancing Soil Health and Plant Growth through Microbial Fertilizers: Mechanisms, Benefits, and Sustainable Agricultural Practices
Soil microorganisms play a crucial role in maintaining the structure and function of soil ecosystems. This study aims to explore the effects of microbial fertilizers on improving soil physicochemical properties and promoting plant growth. The results show that the application of microbial…
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Cooltools: Enabling high-resolution Hi-C analysis in Python
Chromosome conformation capture (3C) technologies reveal the incredible complexity of genome organization. Maps of increasing size, depth, and resolution are now used to probe genome architecture across cell states, types, and organisms. Larger datasets add challenges at each step of computational…
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Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage
BACKGROUND: Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied. METHODS: We randomly…
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Exploring AI-mediated informal digital learning of English (AI-IDLE): a mixed-method investigation of Chinese EFL learners’ AI adoption and experiences
Recent advancements in natural language processing and large language models have ushered language learning into the age of artificial intelligence (AI).Recognizing the affordances of generative AI tools, this paper aims to examine the degree to which L2 learners accepted and leveraged large…
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The Influence of the Global Energy Crisis on Energy Efficiency: A Comprehensive Analysis
The global energy crisis, which began in 2021 due to the extraordinary economic recovery after the pandemic and intensified after Russia’s invasion of Ukraine in February 2022, has changed the conditions of energy management, paying more attention to energy efficiency. Natural gas prices have…
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Long-Term Outcomes of Medical Management vs Bariatric Surgery in Type 2 Diabetes
Importance: Randomized clinical trials of bariatric surgery have been limited in size, type of surgical procedure, and follow-up duration. Objective: To determine long-term glycemic control and safety of bariatric surgery compared with medical/lifestyle management of type 2 diabetes. Design…
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Recent advances in molecular mechanisms of skin wound healing and its treatments
The skin, being a multifaceted organ, performs a pivotal function in the complicated wound-healing procedure, which encompasses the triggering of several cellular entities and signaling cascades. Aberrations in the typical healing process of wounds may result in atypical scar development and the…
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Innovation and challenges of artificial intelligence technology in personalized healthcare
As the burgeoning field of Artificial Intelligence (AI) continues to permeate the fabric of healthcare, particularly in the realms of patient surveillance and telemedicine, a transformative era beckons. This manuscript endeavors to unravel the intricacies of recent AI advancements and their…
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Artikel Jurnal Teks lengkap
Problem Posing as a Learning Model to Improve Primary School Students' Mathematics Learning Outcomes in Gayo Lues
Mathematics is one of the most important subjects for students to master in elementary school. However, there are many students who do not like mathematics learning which has an impact on their low learning outcomes in mathematics learning. The results of the preliminary study of this study…
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