52 hasil untuk "Fu-Rong Li"
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Artikel Jurnal
Long-term exposure to air pollution and risk of incident inflammatory bowel disease among middle and old aged adults
Background: Epidemiological evidence regarding the associations between long-term exposure to air pollution and risk of incident inflammatory bowel disease (IBD) is scant. Objectives: We examined the associations of various specific air pollutants with the risk of incident ulcerative colitis and…
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Artikel Jurnal
Association between secondhand smoke exposure, maternal smoking during pregnancy, and stroke incidence in nonsmokers
Background: To evaluate the independent and combined associations of secondhand smoke (SHS) exposure and maternal smoking during pregnancy with the risk of total stroke and its subtypes, including ischemic and hemorrhagic stroke, among nonsmokers. Objectives: To investigate the independent and…
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Artikel Jurnal
The Effects of Farmyard Manure and Mulch on Soil Physical Properties in a Reclaimed Coastal Tidal Flat Salt-Affected Soil
Careful soil management is important for the soil quality and productivity improvement of the reclaimed coastal tidal flat saline land in northern Jiangsu Province, China. Farmyard manure (FYM) and mulch applications, which affect soil characteristics and plant significantly, are regard as an…
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Artikel Jurnal
Total and Regional Fat/Muscle Mass Ratio and Risks of Incident Cardiovascular Disease and Mortality
Background To evaluate the sex‐specific associations of total and regional fat/muscle mass ratio (FMR) with cardiovascular disease (CVD) incidence and mortality, and to explore the underlying mechanisms driven by cardiometabolites and inflammatory cells. We compared the predictive value of FMRs to…
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Artikel Jurnal
Lipoprotein(a), family history of cardiovascular disease, and incidence of heart failure
Lipoprotein(a) (Lp(a)) is a largely genetically determined biomarker for cardiovascular disease (CVD), while its potential interplay with family history (FHx) of CVD, a measure of both genetic and environmental exposures, remains unclear. We examined the associations of Lp(a) in terms of…
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Artikel Jurnal Teks lengkap
Penicillamine increases free copper and enhances oxidative stress in the brain of toxic milk mice.
Wilson disease (WD) is characterized by the accumulation of copper arising from a mutation in the ATP7B gene. Penicillamine (PA) makes 10-50% of the patients with neurologic symptoms neurologically worse at the early stage of administration. The aim of this study was to determine how the copper…
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Artikel Jurnal Teks lengkap
The immunoregulation effect of alpha 1-antitrypsin prolong β-cell survival after transplantation.
Islet transplantation has considerable potential as a cure for diabetes. However, the difficulties that arise from inflammation and the immunological rejection of transplants must be addressed for islet transplantation to be successful. Alpha 1-antitrypsin (AAT) inhibits the damage on β cells…
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Artikel Jurnal
控制糖尿病心血管风险的行动(ACCORD)试验中的血脂变异性和微血管并发症风险:一项事后分析
Abstract Background Greater lipid variability may cause adverse health events among diabetic patients. We aimed to examine the effect of lipid variability on the risk of diabetic microvascular outcomes among type 2 diabetes mellitus patients. Methods We assessed the association between…
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Artikel Jurnal Teks lengkap
The Relationship between C-Reactive Protein Level and Discharge Outcome in Patients with Acute Ischemic Stroke
Previous studies showed that C-reactive protein (CRP), an inflammatory marker, was associated with stroke severity and long-term outcome. However, the relationship between the acute-phase CRP level and discharge outcome has received little attention. We prospectively studied 301 patients with acute…
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Artikel Jurnal
Derivation of soil Pb/Cd/As thresholds for safety of vegetable planting: A case study for pakchoi in Guangdong Province, China
Regional guidelines for soil heavy metals, in conjunction with specific crops, are proposed to better assess soil environmental quality. In this study, large amounts of soils with different levels of Pb/Cd/As pollution were collected in Guangdong Province, China, to carry out a pot experiment…
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Artikel Jurnal
LSD1 inhibition yields functional insulin-producing cells from human embryonic stem cells
Abstract Background Human embryonic stem cells represent a potentially unlimited source of insulin-producing cells for diabetes therapy. While tremendous progress has been made in directed differentiation of human embryonic stem cells into IPCs in vitro, the mechanisms controlling its…
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Artikel Jurnal
The potential adverse effects of hypodermic glucagon‐like peptide ‐1 receptor agonist on patients with type 2 diabetes: A population‐based study
Abstract Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs), a class of injectable antidiabetic drugs, have shown significant efficacies in improving glycemic and weight control in patients with type 2 diabetes (T2D). However, the long‐term safety of GLP‐1 RAs remains insufficiently…
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Artikel Jurnal Teks lengkap
Early neurological deterioration during the acute phase as a predictor of long-term outcome after first-ever ischemic stroke
Early neurological deterioration (END) is associated with increased risk of functional disability and mortality. However, data are limited regarding the long-term risk of poor functional outcomes. Thus we explored the association between END and long-term outcomes in patients with acute ischemic…
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Artikel Jurnal
Single-cell analyses reveal distinct expression patterns and roles of long non-coding RNAs during hESC differentiation into pancreatic progenitors
Abstract Background Deep understanding the differentiation process of human embryonic stem cells (hESCs) is essential for developing cell-based therapeutic strategy. Substantial efforts have been made to investigate protein-coding genes, yet it remains lacking comprehensive characterization of long…
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Artikel Jurnal
Prevalence and associated factors of sexually transmitted infections among methamphetamine users in Eastern China: a cross-sectional study
Abstract Background The reported incidence of sexually transmitted infections (STIs) in China has been increasing over the last decades, especially among drug users, which has become one of the main burdens of public health in China. This study was conducted to estimate the prevalence and…
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Artikel Jurnal Teks lengkap
H-Type Hypertension and C Reactive Protein in Recurrence of Ischemic Stroke
Hypertension with high homocysteine (HHcy) (H-type hypertension) and C reactive protein (CRP) can increase the incidence of ischemic stroke. However, it is not clear whether recurrent ischemic stroke (RIS) is related to H-type hypertension and CRP. The present study investigated the correlation of…
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Artikel Jurnal
Proteomic analysis reveals LRPAP1 as a key player in the micropapillary pattern metastasis of lung adenocarcinoma
Objectives: Lung adenocarcinomas have different prognoses depending on their histological growth patterns. Micropapillary growth within lung adenocarcinoma, particularly metastasis, is related to dismal prognostic outcome. Metastasis accounts for a major factor leading to mortality among lung…
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Artikel Jurnal
Integrative analysis reveals a lineage-specific circular RNA landscape for adipo-osteogenesis of human mesenchymal stem cells
Abstract Background The balance between osteogenesis and adipogenesis of mesenchymal stem cells (MSCs) is critical to skeletal development and diseases. As a research hotspot, circular RNAs (circRNAs) have expanded our understanding of a hidden layer of the transcriptome. Yet, their roles during…
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Artikel Jurnal
Zinc‐Organometallic Framework Vaccine Controlled‐Release Zn2+ Regulates Tumor Extracellular Matrix Degradation Potentiate Efficacy of Immunotherapy
Abstract Tumor extracellular matrix (ECM) not only forms a physical barrier for T cells infiltration, but also regulates multiple immunosuppressive pathways, which is an important reason for immunotherapy failure. The cyclic guanosine monophosphate‐adenosine monophosphate synthase‐stimulator of…