14 hasil untuk "Hanbin Lin"
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Artikel Jurnal
Continuous video electroencephalogram for herpes simplex encephalitis: a case report and literature review
Abstract Background Electroencephalogram (EEG) is an important tool for the diagnosis of herpes simplex virus encephalitis (HSE). However, the diagnosis of non-convulsive status epilepticus (NCSE) in HSE is challenging without the help of continuous video EEG (CVEEG), and whether EEG is a predictor…
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Artikel Jurnal
Concomitant pulmonary embolism and severe thrombocytopenia associated with an APS-like autoimmune thrombophilic condition: a case report
Abstract Severe thrombocytopenia accompanied by acute pulmonary embolism (PE) represents a rare and challenging clinical scenario, particularly in elderly patients, where both thrombotic and hemorrhagic risks coexist. We report the case of a 78-year-old man who presented with acute dizziness and…
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Artikel Jurnal
Pan‐cancer multi‐omics reveals DCAF7 as an immune‐modulating prognostic driver and Wnt/β‐catenin activator in hepatocellular carcinoma
Abstract Background DDB1 and CUL4‐associated factor 7 (DCAF7) is a WD‐repeat adaptor that recruits substrates to the CUL4DDB1 ubiquitinligase complex, but its pan‐cancer relevance and mechanistic contribution to tumor progression remain unclear. Methods Multi‐omics datasets (genomic…
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Artikel Jurnal
Texture and amino acid changes of Chinese mitten crabs (Eriocheir sinensis) and underpinned physiological and metabolic mechanisms during waterless preservation
This study investigated muscle texture and amino acid changes in Chinese mitten crab (Eriocheir sinensis) during waterless preservation and further explored their relationship with physiological and metabolic profiles. During 6-days waterless preservation, significant reductions in muscle…
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Artikel Jurnal
GLI2-HRD1 axis facilitates 5-FU resistance in gastric cancer cells by regulating ubiquitination degradation of UCK2
5-Fluorouracil (5-FU) is a primary chemotherapeutic agent for treating gastric cancer (GC), yet resistance to 5-FU frequently limits its effectiveness and contributes to poor patient outcomes. This study investigated the molecular mechanisms by which uridine-cytidine kinase 2 (UCK2) influences 5-FU…
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Artikel Jurnal
Comparative study on physiological and metabolic responses of crayfish to ozone micro-nano bubbles and ultrasound washing
Maintaining the well-being of living aquatic products before processing is crucial to guarantee best food quality. This study investigated the different effects of ozone micro-nano bubbles washing (OMW) and ultrasound washing on the well-being of living crayfish, one of the most economically…
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Artikel Jurnal
Knowledge, attitude, and practice of nurses towards frailty syndrome: a multicenter cross-sectional survey in Fujian Province, China
BackgroundFrailty is a global geriatric challenge requiring integrated nursing management. However, the mechanism driving nurses’ practice behaviors remains unclear. This study aimed to evaluate the status of knowledge, attitude, and practice (KAP) regarding frailty syndrome among nurses and…
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Artikel Jurnal Teks lengkap
Recent Advances in the Storage, Transportation, and Quality Control of Eriocheir sinensis: A Review
The Chinese mitten crab (Eriocheir sinensis), as an aquatic food with high economic value, is favored by consumers for its high nutritional value and unique flavor. Its physiological status during temporary rearing and live transportation determines changes in meat quality, nutrition, flavor and…
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Artikel Jurnal
Genome-wide analysis of the bZIP gene family in Cinnamomum camphora ('Gantong 1') reveals the putative function in anthocyanin biosynthesis
Basic leucine zipper (bZIP) transcription factors (TFs) regulate plant development, growth, and secondary metabolism. The formation of red bark of new ornamental cultivar 'Gantong 1' is regulated mainly by anthocyanin anabolism. However, it is unclear whether and which bZIP TFs are involved in this…
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Artikel Jurnal Teks lengkap
Practice and Exploration on the construction of medical affairs management system in large Fangcang hospitals
In view of the difficulties, including simple facilities, temporary team formation, high working intensity, medical safety hazards and difficult emergency disposal etc. in medical management when large-scale Fangcang hospitals admitted and treated large quantity of patients during the epidemic…
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Artikel Jurnal
A nomogram model for predicting seizure control in status epilepticus: development and risk factor analysis
ObjectivesTo explore the risk factors impacting control of seizures in status epilepticus (SE) and to construct a valid nomogram for predicting the prognosis.MethodsIn this retrospective study, we analyzed the patients with SE who were hospitalized in Fujian Medical University Union Hospital from…
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Artikel Jurnal
EEG microstates, spectral analysis, and risk prediction in epilepsy comorbid with mild cognitive impairment: alteration in intrinsic brain activity
Abstract Objective This study aims to investigate the differences in electroencephalogram (EEG) microstates and power spectrum between patients with epilepsy (PWE) comorbid with (without) mild cognitive impairment (MCI) and to develop a machine learning model to predict the risk of MCI comorbidity…
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Artikel Jurnal
The deubiquitinating enzyme OTUD1 antagonizes BH3-mimetic inhibitor induced cell death through regulating the stability of the MCL1 protein
Abstract Background Myeloid cell leukaemia 1 (MCL1) is a pro-survival Bcl-2 family protein that plays important roles in cell survival, proliferation, differentiation and tumourigenesis. MCL1 is a fast-turnover protein that is degraded via an ubiquitination/proteasome-dependent mechanism. Although…
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Artikel Jurnal
USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer
Abstract Metastasis is a major challenge for colorectal cancer (CRC) treatment. In this study, we identified autophagy activation as a prognostic indicator in CRC and observed that the expression of key autophagy proteins is elevated in metastatic and recurrent cases. Our subsequent goal was to…