19 hasil untuk "Qingfeng Fu"
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Artikel Jurnal
hsa_circ_0001018 promotes papillary thyroid cancer by facilitating cell survival, invasion, G1/S cell cycle progression, and repressing cell apoptosis via crosstalk with miR-338-3p and SOX4
We identified a novel interactome, circ_0001018/miR-338-3p/SOX4, in papillary thyroid cancer (PTC), and we intended to confirm the regulatory relationship between the three and to study the effects of the three in PTC. The bioinformatics method was used to screen out the circular RNA and mRNA of…
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Artikel Jurnal
Protocol for in vitro generation of innate lymphoid cells from human embryonic tissues
Summary: Deciphering the origins of innate lymphoid cells (ILCs) is critical for a deeper understanding of innate immunity. Here, we present a protocol for assessing ILC potential of human embryonic resources. We describe steps for identifying lymphoid progenitors in human embryonic tissues, then…
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Artikel Jurnal
The clinical value of repeat ultrasound-guided fine-needle aspiration biopsy in the management of Bethesda Category III thyroid nodules
ObjectiveThis study aimed to evaluate the clinical value of repeat fine-needle aspiration biopsy (rFNAB) for thyroid nodules initially classified as Bethesda Category III, to explore the optimal timing for repeat biopsy, and to optimize the biopsy strategy by integrating ultrasonographic…
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Artikel Jurnal
Pan-cancer analysis reveals the prognostic and immunotherapeutic value of cytoskeleton-associated protein 2-like
Abstract Cytoskeleton-associated protein 2-like (CKAP2L), a cell cycle-related protein, is correlated to tumor progression in some tumors. But there were no pan-cancer studies on CKAP2L, and its role in cancer immunotherapy is also unclear. The expression levels, expression activity, genomic…
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Artikel Jurnal
Reshaping the colorectal cancer immune microenvironment: insights from single-cell and spatial omics
Abstract Colorectal cancer (CRC) remains a significant global health challenge, ranking among the leading causes of cancer-related morbidity and mortality. Accumulating evidence indicates that disease progression and therapeutic resistance in CRC are not solely tumor cells but are critically shaped…
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Artikel Jurnal
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells
Abstract Stem cell (SC) therapy has been shown high prospects in erectile dysfunction (ED) treatment. Without ethical issues and risks of immune rejection and tumorigenesis of exogenous SC therapy, endogenous stem/progenitor cells (S/PCs) have a better potential for ED management, and their homing…
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Artikel Jurnal
LncRNA FOXD2-AS1 Functions as a Competing Endogenous RNA to Regulate TERT Expression by Sponging miR-7-5p in Thyroid Cancer
Long non-coding RNA FOXD2 Adjacent Opposite Strand RNA 1 (FOXD2-AS1) has been widely reported to be implicated in the progression and recurrence of several cancers. The clinical significance and functional role of FOXD2-AS1 in thyroid carcinoma remain unknown. FOXD2-AS1 expression was evaluated by…
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Artikel Jurnal
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism
Abstract Background Prostate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which lacks effective treatment measures. PTENP1, a long non-coding RNA, has been shown to suppress tumor growth through the rescuing of PTEN…
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Artikel Jurnal Teks lengkap
When cytology misses and ultrasound warns: the predictive role of BRAFV600E mutation in thyroid nodules
PURPOSE: Thyroid nodules with high-suspicion ultrasound features but benign cytologic findings remain a diagnostic challenge due to potential false-negative fine-needle aspiration (FNA) results. The BRAFV600E mutation, a hallmark of papillary thyroid carcinoma (PTC), may improve malignancy risk…
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Artikel Jurnal
ESCO2’s oncogenic role in human tumors: a pan-cancer analysis and experimental validation
Abstract Purpose Establishment of sister chromatid cohesion N-acetyltransferase 2 (ESCO2) is involved in the mitotic S-phase adhesins acetylation and is responsible for bridging two sister chromatids. However, present ESCO2 cancer research is limited to a few cancers. No systematic pan-cancer…
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Artikel Jurnal
Accurate quantification of TiO2(B)'s phase purity via Raman spectroscopy
Bronze phase titanium dioxide (TiO2(B)) could be a promising high-power anode for lithium ion battery. However, TiO2(B) is a metastable material, so the as-synthesized samples are inevitably accompanied by the existence of anatase phases. It has been found that the TiO2(B)'s purity is positively…
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Artikel Jurnal
Diagnostic performance of Midkine ratios in fine-needle aspirates for evaluation of Cytologically indeterminate thyroid nodules
Abstract Background Fine-needle aspiration cytology (FNAC) is a basic diagnostic tool for thyroid nodules. However, 15–30% of nodules are cytologically indeterminate. Midkine (MK), a pleiotropic growth factor, is often upregulated in patients with cancers. This study aimed to evaluate the role of…
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Artikel Jurnal
Associations of cumulative exposure and two-time-point clustering of the triglyceride-cholesterol-body weight index with incident cardiovascular disease in middle-aged and older Chinese adults: a nationwide cohort study
Abstract Aims The triglyceride-cholesterol-body weight index (TCBI) has been proposed as a biomarker of the prognosis of stroke. However, the relationship between cumulative exposure and dynamic trajectories of the TCBI (cuTCBI/TCBI changes) and the risk of cardiovascular disease (CVD) remains…
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Artikel Jurnal
Decoding innate lymphoid cell heterogeneity and plasticity in colorectal cancer
Abstract Background In colorectal cancer (CRC), innate lymphoid cells (ILCs) play a vital role in preserving and modulating immune homeostasis within the intestinal environment. However, the origins and diverse functions of ILCs in CRC remain poorly understood, making it difficult to clarify how…
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Artikel Jurnal
2D Titanium carbide printed flexible ultrawideband monopole antenna for wireless communications
Designing ultrathin and flexible antenna is of great interest for efficient wireless data communication and transmission at fast-growing IoT applications. The authors report a flexible ultrawideband Ti3C2 monopole antenna by combining strategies of interfacial modification and advanced extrusion…
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Artikel Jurnal
Long Non-Coding RNA MAPK8IP1P2 Inhibits Lymphatic Metastasis of Thyroid Cancer by Activating Hippo Signaling via Sponging miR-146b-3p
The principal issue derived from thyroid cancer is its high propensity to metastasize to the lymph node. Aberrant exprssion of long non-coding RNAs have been extensively reported to be significantly correlated with lymphatic metastasis of thyroid cancer. However, the clinical significance and…
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Artikel Jurnal
A novel risk stratification model based on tumor size and multifocality to predict recurrence in pediatric PTC: comparison with adult PTC
BackgroundPediatric papillary thyroid cancer presents with a more advanced stage of disease than adult PTC; and it is more likely to be aggresive and distant metastases, although the survival rate is high.MethodsA retrospective observational study was performed in children and adults with PTC…
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Artikel Jurnal
Anatomical location matters: risk modelling and surgical outcomes in central lymph node metastasis of isthmus PTC
BackgroundIsthmus papillary thyroid carcinoma (iPTC) represents a distinct clinical entity with a higher propensity for central lymph node metastasis (CLNM) and greater local aggressiveness compared to lobe-confined PTC. Despite increasing recognition of its unique risk profile, controversy…