13 hasil untuk "Guang-Rui Wang"
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Artikel Jurnal Teks lengkap
Hypoxia microenvironment promotes invasion and proliferation of human breast cancer cell line MCF-7
Objective To investigate the expression of HIF-1 α, PAR-1 and VEGF in breast cancer tissues from patients with type 2 diabetes and the effect of hypoxia microenvironment on the invasion and proliferation of human breast cancer cell line (MCF-7). Methods Thirty-seven specimens of breast cancer from…
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Artikel Jurnal
Multi-omics in immunotherapy research for HNSCC: present situation and future perspectives
Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, significantly impacting patient survival and quality of life. The recent emergence of immunotherapy has provided new hope for HNSCC patients, improving survival rates; however, only 15%–20% of patients…
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Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway–Dependent Cerebral Microvascular Protection
Stroke is one of the most devastating diseases worldwide. The Chinese herbal preparation SaiLuoTong (SLT) capsule showed outstanding therapeutic effects on stroke and its sequelae. The aim of this study was to further elucidate its therapeutic mechanism. We duplicated a permanent cerebral ischemia…
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Artikel Jurnal
Triaptosis and Cancer: Next Hope?
Cancer persists as one of the most formidable global public health crises and socioeconomic burdens of our era, compelling the scientific community to develop innovative and diversified therapeutic modalities to revolutionize clinical management and enhance patient outcomes. The recent seminal…
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Artikel Jurnal Teks lengkap
Development of a Pixel-Wise Forest Transmissivity Model at Frequencies of 19 GHz and 37 GHz for Snow Depth Inversion in Northeast China
Satellite passive microwave remote sensing has been extensively used to estimate snow depth (SD) and snow water equivalent (SWE) across both regional and continental scales. However, the presence of forests causes significant uncertainties in the estimations of snow parameters. Forest…
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Artikel Jurnal
Histochemistry of microinfarcts in the mouse brain after injection of fluorescent microspheres into the common carotid artery
The mouse model of multiple cerebral infarctions, established by injecting fluorescent microspheres into the common carotid artery, is a recent development in animal models of cerebral ischemia. To investigate its effectiveness, mouse models of cerebral infarction were created by injecting…
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Artikel Jurnal
Metal-dependent cell death resistance contribute to lymph node metastasis of oral squamous cell carcinoma
ObjectivesFerroptosis and cuproptosis can be summarized as metal-dependent cell death. This study aimed to explore the expression of metal-dependent cell death resistance (MCDR) characteristics in tumor cells of oral squamous cell carcinoma (OSCC) and to explore its relationship with lymph node…
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Artikel Jurnal
Adjuvants for cancer mRNA vaccines in the era of nanotechnology: strategies, applications, and future directions
Abstract Research into mRNA vaccines is advancing rapidly, with proven efficacy against coronavirus disease 2019 and promising therapeutic potential against a variety of solid tumors. Adjuvants, critical components of mRNA vaccines, significantly enhance vaccine effectiveness and are integral to…
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Artikel Jurnal
Cuproptosis-based nanomedicine in cancer metastasis synergistic therapy
Cancer metastasis is a critical indicator of cancer progression and serves as a major cause of cancer-related deaths. Cuproptosis is a novel form of regulated cell death proposed in 2022. Unlike ferroptosis and other known regulated cell deaths (RCDs), cuproptosis has a unique regulatory pathway…
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ORL@Cu‐MOF Boost Cuproptosis and Suppress Fatty Acid Metabolism for Cancer Lymph Node Metastasis Synergistic Therapy
Abstract Lymph node metastasis (LNM) is one of the significant characteristics of poor prognosis in oral squamous cell carcinoma (OSCC), strongly associated with high mortality rates. Immunotherapy has emerged as a crucial treatment modality for OSCC LNM, yet its limited response rate severely…
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Artikel Jurnal
Emerging roles of microfluidics in oral cancer research and clinical translation
Oral cancer remains a global health burden, with limited improvements in long-term survival despite advances in multimodal therapy. Advances in early diagnosis and treatment strategies for oral cancer patients will significantly improve survival outcomes. Microfluidic technology, with its capacity…
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Artikel Jurnal
Burnout among dental students: a systematic review and meta-analysis
Abstract Objective Burnout among dental students has been associated with detrimental effects on their mental health and educational outcomes. This systematic review aims to evaluate the prevalence of burnout in this group. Methods A comprehensive search was performed in PubMed, Web of Science…
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Artikel Jurnal
Lymph node metastasis diagnosis of postoperative OSCC patients by analyzing extracellular vesicles in drainage fluid based on microfluidic isolation
Abstract Lymph node metastasis (LNM) is a typical marker in oral squamous cell carcinoma (OSCC) indicating poor prognosis. Pathological examination by artificial image acquisition and analysis, as the main diagnostic method for LNM, often takes a week or longer which may cause great anxiety of the…